Syrris are proud to introduce the Asia, a new range of advanced flow chemistry systems. With a completely flexible and modular design, the Asia can be configured to meet the individual needs of any chemist and can be easily upgraded to meet changing demands.

The Asia offers maximum chemical resistance and features an extensive range of temperatures, pressures and reaction times on scales from mg to kg. Syrris have developed three variations of the Asia, each are available in three different models which have been pre-configured for varying levels of functionality.

Series 1 (manual) - A robust, totally chemically resistant micoreactor system for solution phase chemistry. Ideal for chemists with a lower budget or those who prefer not to have automation. The series 1 has a temperature range of -15oC to 150oC and a pressure rate of 300 psi.

Model 110 - Contains 2 chemically resistant ultra smooth pump channels, a glass microreactor with heater & cooler and back pressure controller for super heating

Model 120 - Contains the same features as the 110 as well as a high temperature microreactor heater, solid phase chemistry reactors & heater adaptor and a preparative scale tube reactor & heater adaptor

Model 130 - Contains the same features as the 120 as well as inert solvent/reagent storage, 2 automated reagent injection loops and a product collector.

Series 2 (Automatic) - Designed to automatically perform one experiment at a time. Parameters such as reaction temperature, pressure, reagent injections and collection timings are all automated. The series 2 is ideal as an introduction to flow synthesis

Model 210 - Contains the same features as the 110 as well as inert solvent/reagent storage, a product collector and automation of reaction conditions and collection.

Model 220 - Contains the same features as the 210 as well as 2 automated reagent injection loops, a high temperature microreactor heater, solid phase chemistry reactors & heater adaptor and a preparative scale tube reactor & heater adaptor.

Model 230 - Contains the same features as the 220 as well as 2 additional pump channels, 2 additional injection loops, flow aqueous work-up and full PC software control

Series 3 (Automatic) - Fully automated collection of multiple multi-step reactions in solution or solid phase. Automatically perform process optimisation. Parameters such as reaction time, temperature and ratio of reagents can be varied and each reaction collected and analysed automatically. The series 3 has a temperature range of -15oC to 250oC and a pressure rate of 300 psi.

Model 310 - Contains the same features as the 110 as well as inert solvent/reagent storage, 2 automated reagent injection loops, automation of reaction conditions and automated collector of multiple samples

Model 320 - Contains the same features as the 310 as well as 2 additional pump channels, 2 additional injection loops, a high temperature microreactor heater, solid phase chemistry reactors & heater adaptor, preparative scale tube reactor & heater adaptor and full PC software control.

Model 330 - Contains the same features as the 320 as well as a flow aqueous work-up and automated sampler & diluter for online analysis.

Asia's innovative Syringe Pump comes standard with all models.

For further information please call 1800 251 799 or email info@johnmorris.com.au

Syrris are pleased to introduce the Asia Pump, an ultra smooth syringe pump for flow chemistry. The Asia has a rating of 20 bar (300 psi) and is extremely chemically resistant with all wetted surfaces made of glass or PTFE (and other fluorinated polymers).

The Asia pump features two independent continuous flow channels, each with an integrated pressure sensor and a flow rate range from 1.0 µl to 10 ml/min. With the ability to provide an extremely smooth flow rate and a width of only 23 cm, the Asia is ideal for in-lab use.

Produced to the highest specification, the flow rate and volume can be easily controlled by the intuitive front panel (twist and click control knob) or the Asia PC software. The PTFE pressure sensor ensures safe operation by automatically stopping the pumps in the case of over pressure.

Components such as valves, syringes and pressure sensors are quick and easy to attach as they clip in and out without tools.

For further information on the Asia Pump please call 1800 251 799 or email info@johnmorris.com.au

Syrris’ Atlas Software is an easy to use computer based application for reaction control and data capture from experiments. The software is designed to be intuitive and easy to use:

- Design you apparatus - allows a range of third party equipment to be automated as part of your experiment

- Design your method - allows a range of controlled steps to be undertaken either sequentially or simultaneously

- Run your experiment - monitor, interrupt, change or adapt your experiment as you go along knowing that any changes will be saved together with the experiment data

The Atlas software is supplied with a range of useful template experiments. Atlas software will control and monitor all experiment parameters in real time and automatically log data to a file. The recipe can be paused at any point with full on the fly editing.

The software includes comprehensive alarms and fail-safe checking. In-built recipe protection prevents operation outside user specified parameters.

Data such as temperature, speed and mass flow can be graphed and monitored in real time and continually saved to one CSV data file making analysis easy. Featuring a drag and drop interface recipes can be created, changed and saved with the click of a mouse.

As well as the Syrris Atlas, products from other manufacturers such as stirrers, balances, pumps and circulators can also be integrated. Most RS232 devices with ASCII communications can be connected to the software via port which plugs into the computer’s USB connection.

The Syrris Orbit Parallel Reaction Station is a high performance, low cost parallel synthesis system for research and development chemistry.

The orbit fits on an Atlas hot plate, Atlas hot/cold plate or a regular hotplate with magnetic stirring. The reaction tubes may be heated to 280°C with reflux, or cooled to -40°C.

The Orbit is available in two sizes

-The Orbit 6 which can hold six tubes (24mm Ø, 45ml)

-The Orbit 12 which can hold twelve tubes (13mm Ø, 10ml)

The Orbit consists of two parts. The Orbit has a ‘twist and click’ lid. When the Orbit lid is closed, it will immediately introduce any desired (inert) atmosphere to all reaction tubes. When the lid is removed, the septa sealing each reaction tube automatically re-seals and the tubes can be safely transported with any risk of exposure to air/moisture vapour. (Note, the built-in reaction tube septa also enables the introduction of reagents under inert conditions.)

The Orbit base is called the Refux Unit. The reaction tubes can be lifted in and out of the Reflux Unit. This enables the reaction tubes to be freely transported as one unit whilst the cooling/heating circulator line and reagent/inert gas in-let line remain connected to the Reflux Unit.

Syrris has introduced an easy to use flow chemistry experimental system, the FRX. With the FRX, reactions occur under laminar flow conditions, improving reaction speed, optimisation and control. The FRX flow chemistry systems are modular, allowing chemists to select the system that best meets individual needs and can be easily upgraded to meet changing demands.

The FRX is small in size and easily fits into the laboratory workplace.

Four modular FRX systems are offered by Syrris which have a range of functionalities and offer simple manual mode operation from the instrument’s front panel. The systems also allow both a solid and solution phase chemistry to be performed, expanding the range of reaction types that can be carried out in flow. Furthermore, high pressure capabilities permit the super heating of solvents and further increase reaction speed.

Modularity provides flexibility and easy integration of the units for increased reaction steps or more complex set ups when required. Wide flow range pump and reaction heating systems enable multiple reaction conditions to be run. Additionally analysis can be undertaken throughout the reaction by manually diverting a small quantity of the reaction mixture for testing and characterisation.

The FRX systems range from the basic 100, designed for initial flow chemistry work using a larger volume tube reactor and the 200, with a micro reactor and solid phase column – to the more complex FRX 300 and 400 for multi step chemistry and more complex set ups. Both the 300 and 400 incorporate an FRX Liquid – Liquid Extraction module (FLLEX). The FLLEX facilities compound purification and separation post reaction, which once separated can be passed for collection, analysis or further reaction. The FRX 400 also allows reaction cooling and can be used with solid supported chemistries.

Syrris has introduced a high performance multipurpose synthesis system for research and development chemists, the Atlas. The Atlas offers a modular solution for a range of functions including heating, stirring, cooling and automated reagent addition.

The Atlas can adopt a wide range of different system configurations:

The Lithium system automates reactions in round bottomed flasks or vials and is equipped with a Hotplate and Stacking Dry Bath. Flasks from 50ml to 1 litre can be heated up to 280°C while the exterior surface remains cool to the touch. The Lithium allows users to edit and run profiles automatically from the base to control heating, cooling, stirring and reagent addition.

The Sodium system automates reactions in round bottomed flasks and is equipped with a hotplate (or Hot & Coldplate), magnetic stirrer and a Scorpion Overhead Stirrer for viscous reactions. The Stacking Dry Bath enables heating of round bottom flasks from 50ml to 1 litre up to 280°C

The Potassium system is designed for chemists who perform reactions in jacketed reactors. Integrated temperature and circulator control from the base unit make reactions easier. The Potassium is equipped with a scorpion Overhead Stirrer and 250ml round bottom Jacketed Vessel which can be substituted if required.

The pH Monitoring and Control systems are ideal for chemists who perform pH sensitive reactions. The pH system is based on the Potassium although the temperature node is replaced with a combined pH & temperature node and a pH probe allowing the Atlas to monitor both reaction temperature and pH. The pH system is equipped with a Syringe pump and can be configured to control the pH of a reaction by adding either acid and/or base as necessary to maintain a set pH value. The pH system can be operated from the Base Unit or via the Atlas Software.

The Remote Mount is designed for chemists who perform reactions in jacketed vessels. The Remote Mount allows a vessel to be mounted onto laboratory scaffolding. The Mount adds functionality to existing Atlas Systems by increasing the maximum working volume to 5 litres and locating jacketed vessels away from the Atlas Base.

The Gravimetric Dosing system allows a defined mass of reagent to be pumped from a balance to the reactor by a controlled peristaltic pump. The mass flow rate can be defined, monitored and adjusted by using Atlas Software.

The Syringe Pump is a volumetric dosing system which consists of two syringes and can be configured into two refilling flows or one continuous flow. A choice of dosing modes allows simple additions or active control of parameters including pH and temperature.

Atlas Software is an easy to use application for control and analysis of experiments. Systems including stirrers, circulators, RTD’s, pumps, balances, flow meters etc. The Software controls Atlas hardware as well as devices from other manufacturers. Reactions are continuously monitored and graphed with easy to use alarms and emergency control.